Clinical Research & Trials

The Pepose Vision Institute operates one of the most influential ophthalmologic research facilities in the country. It has played a key role in FDA – approved clinical studies leading to the introduction of such ground breaking technologies as Lasik Surgery, Crystalens for cataracts and more.

Clinical research and trials at Pepose Vision Institute are administered by the Lifelong Vision Foundation to fund independent vision research projects, community programming, and education.

These studies offer a great opportunity for our patients to receive the most advanced vision treatment possible, generally years before the general public, and often at a discounted price and/or with other benefits such as compensation for your time.

If you are interested in cataract surgery, LASIK Vision Correction, have age-related macular degeneration, dry eyes or any other vision issue, please continue reading to learn how you can benefit from participating in one of our studies.



What are clinical studies?

Clinical studies are research studies used for FDA-approved procedures and products, such as LASIK and Crystalens, or studies performed for FDA approval. Most studies require a longer patient time commitment to effectively measure the progress. In exchange for this time commitment, patients are often offered these procedures and/or products at a reduced price. Our clinical studies not only play an important role in the development of important vision advances, but are also an ideal opportunity for patients to receive the best and latest vision correction possible at a reduced cost.

How can you participate?

Our clinical studies often offer patients access to the latest technologies, when there is a cost, discounted services and possible compensation for your time. All clinical studies are conducted at Pepose Vision Institute under the guidance of Dr. Jay Pepose.

Take a look at our current studies listed below.  If you find a study you are interested in, here’s how you can learn more and possibly participate:

• To get started, contact Lifelong Vision Foundation by either completing our Clinical Studies Application or call (636) 534-5126.

• Your information will then be reviewed to see if you pre-qualify for one of our studies. Upon reviewal, we will contact you to schedule a consultation.

• At your initial consultation, we will perform a series of eye tests and measurements, review your information and ask additional questions.

• Based on the results of your consultation, if you qualify for a study we will explain the study in further detail and answer any questions – including the exact procedure, commitments and costs or compensation.

• Should you find a study of interest, we will schedule your procedure and follow visits.

LVF Logo

The clinical studies offered through Pepose Vision are administered by the Lifelong Vision Foundation, a not-for-profit organization established to support research efforts in ophthalmology, to educate physicians and the general public in the diagnosis and treatment of ocular disease, and to provide vision screening and treatment programs for specific underserved communities. Please visit to learn more.

Current studies

We have conducted and continue to conduct clinical studies in LASIK vision correction, cataract removal, age-related macular degeneration and other retinal services, dry eye treatment and more. We are continually evaluating research opportunities for new advanced eye treatments under review by the Food and Drug Administration (FDA) and are adding new studies on a regular basis.
Click here to see our current studies


“I wasn’t sure what to expect and to be honest was a bit scared, but Dr. Pepose and his staff made me feel comfortable the entire time. They explained things in detail (over and over since I really wanted to understand) and had so much patience. I couldn’t be happier with my vision.”  Beth

“I wanted to get Lasik but didn’t think I could afford a high quality surgeon. After learning about the study I not only was able to get my surgery at a bit of a discount, but even better I got a new type of Lasik that no one else would be able to get for at least another year or two. My eye sight is still great.”  Ryan

“I had to do something about my cataracts. When they explained Crystalens to me I was amazed – no more glasses! The entire process went great – I did have a couple more exams than I think normal cataract patients have but it was so worth it. And I played a part in making Crystalens available to the world.”  Sara

Come see us for all your vision needs

If you are interested in learning more about our studies, have any vision issues or haven't had a general eye exam in a while, please come see us. Our experienced doctors will use advanced diagnostics to determine exactly how to best help you see your very best, patiently answer your questions and carefully explain all your options.

Contact us